New psychoactive substances: a review and updates Abu Shafi, Alex J. Berry, Harry Sumnall, David M. Wood and Derek K. Tracy Therapeutic Advances in Psychopharmacology, 2020, Vol. 10, 1–21. Doi : 10.1177/2045125320967197 Abstract : New psychoactive substances (NPS) are a heterogeneous group of substances. They are associated with a number of health and social harms on an individual and societal level. NPS toxicity and dependence syndromes are recognised in primary care, emergency departments, psychiatric inpatient and community care settings. One pragmatic classification system is to divide NPS into one of four groups: synthetic stimulants, synthetic cannabinoids, synthetic hallucinogens and synthetic depressants (which include synthetic opioids [...]
Lire la suiteMolecular Mechanisms of Action of Novel Psychoactive Substances (NPS). A New Threat for Young Drug Users with Forensic-Toxicological Implications Arianna Giorgetti, Jennifer P. Pascali, Paolo Fais, Guido Pelletti, Andrea Gabbin, Giorgia Franchetti, Giovanni Cecchetto and Guido Viel Life, 2021, 11, 440, 1-17. doi : 10.3390/life11050440 Abstract : Novel psychoactive substances (NPS) represent a severe health risk for drug users. Even though the phenomenon has been growing since the early 2000s, the mechanisms of action of NPS at the receptors and beyond them are still scarcely understood. The aim of the present study was to provide a systematic review of the updated knowledge regarding the molecular [...]
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