LSD Increases Primary Process Thinking via Serotonin 2A Receptor Activation Rainer Kraehenmann, Dan Pokorny, Helena Aicher, Katrin H. Preller, Thomas Pokorny, Oliver G. Bosch, Erich Seifritz and Franz X. Vollenweider Frontiers in Pharmacology, 2017, Volume 8, Article 814, 1-9. Doi : 10.3389/fphar.2017.00814 Rationale : Stimulation of serotonin 2A (5-HT2A) receptors by lysergic acid diethylamide (LSD) and related compounds such as psilocybin has previously been shown to increase primary process thinking – an ontologically and evolutionary early, implicit, associative, and automatic mode of thinking which is typically occurring during altered states of consciousness such as dreaming. However, it is still largely unknown whether LSD induces [...]
Lire la suiteLSD enhances suggestibility in healthy volunteers R. L. Carhart-Harris, M. Kaelen, M. G. Whalley, M. Bolstridge, A. Feilding, D. J. Nutt Psychopharmacology, 2014 DOI 10.1007/s00213-014-3714-z Abstract Rationale : Lysergic acid diethylamide (LSD) has a history of use as a psychotherapeutic aid in the treatment of mood disorders and addiction, and it was also explored as an enhancer of mind control. Objectives : The present study sought to test the effect of LSD on suggestibility in a modern research study. Methods : Ten healthy volunteers were administered with intravenous (i.v.) LSD (40–80 μg) in a within-subject placebocontrolled design. Suggestibility and cued mental imagery were assessed using the Creative [...]
Lire la suitePsychedelics and hypnosis : Commonalities and therapeutic implications Clément E. Lemercier, Devin B. Terhune Journal of Psychopharmacology, 2018, 32, 7, 732-740. DOI : 10.1177/0269881118780714 Abstract Background : Recent research on psychedelics and hypnosis demonstrates the value of both methods in the treatment of a range of psychopathologies with overlapping applications and neurophenomenological features. The potential of harnessing the power of suggestion to influence the phenomenological response to psychedelics toward more therapeutic action has remained unexplored in recent research and thereby warrants empirical attention. Aims : Here we aim to elucidate the phenomenological and neurophysiological similarities and dissimilarities between psychedelic states and hypnosis in order to revisit [...]
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