Neuroprotection by cannabidiol and hypothermia in a piglet model of newborn hypoxic-ischemic brain damage Lorena Barata⁠a, ⁠ Luis Arruza⁠, Maria-José Rodríguez⁠, Esther Aleo⁠, Eva Vierge⁠, Enrique Criado⁠, Elena Sobrino⁠, Carlos Vargas⁠, María Ceprián⁠⁠,  Ana Gutiérrez-Rodríguez⁠, William Hind⁠, José Martínez-Orgado⁠ Neuropharmacology, 2018. https://doi.org/10.1016/j.neuropharm.2018.11.020   A B S T R A C T Objective : Hypothermia, the gold standard after a hypoxic-ischemic insult, is not beneficial in all treated newborns. Cannabidiol is neuroprotective in animal models of newborn hypoxic-ischemic encephalopathy. This study compared the relative efficacies of cannabidiol and hypothermia in newborn hypoxic-ischemic piglets and assessed whether addition of cannabidiol augments hypothermic neuroprotection. Methods : One day-old HI (carotid clamp and FiO⁠2 10% for 20min) [...]