The EU CBD CONSUMER REPORT SERIES : Segmentation & Archetypes Executive Summary, Volume II New Frontier Data 2019-2020, European CBD Survey, 7 pp. As the active ingredient cannabidiol (CBD) from cannabis has undergone an explosive growth in popularity, consumers in the European Union (EU) are increasingly being exposed to information and products—and trying to understand the cannabinoid’s potential and how it might best fit into their lives. As of February 2020, within the EU’s 27 member states, its 445 million citizens find increasing opportunities to participate in the burgeoning CBD market, and brands will play a critical role in defining their experiences. Having already [...]
Lire la suiteInteraction of maternal choline levels and prenatal Marijuana's effects on the offspring Camille Hoffman, Sharon K. Hunter, Angelo D'Alessandro, KathleenNoonan et al. Psychological Medicine, 2019 Doi : https://doi.org/10.1017/S003329171900179X Published online by Cambridge University Press: 31 July 2019 Abstract Background : This study investigated whether higher maternal choline levels mitigate effects of marijuana on fetal brain development. Choline transported into the amniotic fluid from the mother activates α7-nicotinic acetylcholine receptors on fetal cerebro-cortical inhibitory neurons, whose development is impeded by cannabis blockade of their cannabinoid-1(CB1) receptors. Methods : Marijuana use was assessed during pregnancy from women who later brought their newborns for study. Mothers were informed about [...]
Lire la suiteCannabis and the developing brain : Insights from behavior Viviana Trezza, Vincenzo Cuomo, Louk J.M.J. Vanderschuren European Journal of Pharmacology, 2008, 585, 441-452. Doi : 10.1016/j.ejphar.2008.01.058 A B S T R A C T The isolation and identification, in 1964, of delta-9-tetrahydrocannabinol (THC), the primary psycho-active compound in cannabis, opened the door to a whole new field of medical research. The exploration of the therapeutic potential of THC and other natural and synthetic cannabinoid compounds was paralleled by the discovery of the endocannabinoid system, comprising cannabinoid receptors and their endogenous ligands, which offered exciting new insights into brain function. Besides its well-known involvement in specific [...]
Lire la suiteProlonged Cannabidiol Treatment Lacks on Detrimental Effects on Memory, Motor Performance and Anxiety in C57BL/6J Mice Eva M. Schleicher, Frederik W. Ott, Melanie Müller, Barbara Silcher, Marius E. Sichler, Maximilian J. Löw, Jannek M. Wagner and Yvonne Bouter Frontiers in Behavioral Neuroscience, 2019, Volume 13, Article 94 doi : 10.3389/fnbeh.2019.00094 The Cannabis plant contains more than 100 currently known phytocannabinoids. Regarding the rising consumption of the non-psychotropic phytocannabinoid cannabidiol (CBD) in people’s everyday life (e.g., beauty products, food and beverages), the importance of studies on the influence of CBD on healthy humans and rodents is evident. Therefore, the behavioral profile of CBD was investigated with [...]
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