An epidemiological, developmental and clinical overview of cannabis use during pregnancy Hanan El Marroun, Qiana L. Brown, Ingunn Olea Lund, Victoria H. Coleman-Cowger, Amy M. Loree, Devika Chawlaj, Yukiko Washio Preventive Medicine, 2018, 116, 1–5 Doi : 10.1016/j.ypmed.2018.08.036 A B S T R A C T The objective of the current narrative literature review is to provide an epidemiological, developmental and clinical overview on cannabis use during pregnancy. Cannabis use in pregnancy poses major health concerns for pregnant mothers and their developing children. Although studies on the short- and long-term consequences of prenatal cannabis exposure are increasing, findings have been inconsistent or difficult to interpret [...]
Lire la suiteCannabis use and the course and outcome of major depressive disorder : A population based longitudinal study FEINGOLD D., REHM J., LEV-RAN S. Psychiatry Research, 2017, 251, 225-234. Doi : 10.1016/j.psychres.2017.02.027 Highlights • Individuals with baseline major depressive disorder were followed over a three-year time period. • Cannabis users and individuals with cannabis use disorders were compared to nonusers. • No differences were found in rates of remission between the groups. • Level of cannabis use was associated with significantly more depressive symptoms at follow-up. • These findings did not retain significance after adjusting for baseline confounding factors. Abstract Cannabis use has been reported to affect [...]
Lire la suiteMapping cannabis potency in medical and recreational programs in the United States Mary Catherine Cash, Katharine Cunnane, Chuyin Fan, E. Alfonso Romero-Sandoval PLoS ONE, 2020, 15, (3), e0230167. Doi : 10.1371/journal.pone.0230167 Opinion d'expert: Les allégations sur l'infaisabilité du cannabis avec des concentrations élevées de THC à des fins médicales ne sont pas étayées par la science En mars 2020, le conseil d'administration de l'IACM a décidé d'installer une nouvelle catégorie dans le Bulletin de l’IACM, qui encourage à rédiger des opinions et des déclarations de chercheurs sur les rapports scientifiques actuels et des déclarations de collègues. Ces avis visent à stimuler la discussion sur [...]
Lire la suiteConfinement et cannabis, cachez cette addiction que le gouvernement ne saurait voir Jean-Yves Nau — 2 avril 2020 à 7h00 SLATE http://www.slate.fr/story/189123/addictions-cannabis-confinement-coronavirus-deni-consequences-dependance Tabac, alcool et produits de vapotage n'ont heureusement pas été interdits. Mais il va falloir compter avec les multiples conséquences de la pénurie en cannabis. «Une dépendance grave à une substance licite vaut toujours mieux qu'une dépendance de moindre gravité à une substance interdite», déplore le Dr William Lowenstein, président de SOS Addictions. | Il croyait très bien faire. Lundi 23 mars, Ziad Khoury, préfet de l'Aisne, prenait un arrêté interdisant toutes les ventes d'alcool à emporter dans l'ensemble du département. Objectif: réduire les [...]
Lire la suiteCannabis Use Disorder and Perioperative Outcomes in Major Elective Surgeries A Retrospective Cohort Analysis Akash Goel, M.D., M.P.H., Brandon McGuinness, M.D.; Naheed K. Jivraj, M.B.B.S., M.Sc.; Duminda N. Wijeysundera, M.D., Ph.D.; Murray A. Mittleman, M.D., Dr.P.H.; Brian T. Bateman, M.D., M.Sc., Hance Clarke, M.D., Ph.D.; Lakshmi P. Kotra, B.Pharm. (Hons), Ph.D.; Karim S. Ladha, M.D., M.Sc. Anesthesiology, 2020, 132, (4), 625-635. Abstract and Introduction Background: Although cannabis is known to have cardiovascular and psychoactive effects, the implications of its use before surgery are currently unknown. The objective of the present study was to determine whether patients with an active cannabis use disorder have an elevated [...]
Lire la suiteCannabidiol regulates behavioural alterations and gene expression changes induced by spontaneous cannabinoid withdrawal Francisco Navarrete, Auxiliadora Aracil-Fernández and Jorge Manzanares British Journal of Pharmacology, 2018. Doi : 10.1111/bph.14226 BACKGROUND AND PURPOSE Cannabidiol (CBD) represents a promising therapeutic tool for treating cannabis use disorder (CUD). This study aimed to evaluate the effects of CBD on the behavioural and gene expression alterations induced by spontaneous cannabinoid withdrawal. EXPERIMENTAL APPROACH Spontaneous cannabinoid withdrawal was evaluated 12 h after cessation of CP-55,940 treatment (0.5 mg·kg1 every 12 h, i.p.; 7 days) in C57BL/6J mice. The effects of CBD (5, 10 and 20 mg·kg1, i.p.) on withdrawal-related behavioural signs were evaluated by [...]
Lire la suiteIs cannabis an effective treatment for anxiety disorders ? https://www.anxiety.org/is-cannabis-an-effective-treatment-for-anxiety-what-research-shows Lindsey Salerno, M.Ed. from Philadelphia College of Osteopathic Medicine Jesse McCann, B.S. from University of Pennsylvania, School of Medicine Shari Lieblich, B.S. from University of Pennsylvania, School of Medicine Jeremy Tyler, Psy.D. from University of Pennsylvania Is cannabis really an effective treatment for anxiety? Research and evidence shows mixed results so learn the facts here and consult a professional. Facts v. Fiction: What the research says What is cannabis (marijuana)? What are common misconceptions? Yes - cannabis can be an effective anxiety treatment - but the opposite is also true Participate in a clinical trial [...]
Lire la suiteMarijuana Use Continues to Grow in Older Adults Pauline Anderson Medscape, February 26, 2020 https://www.medscape.com/viewarticle/925762?nlid=134178_2052&src=WNL_mdplsnews_200228_mscpedit_psyc&uac=292598PZ&spon=12&impID=2294726&faf=1 Cannabis use in older Americans is growing. New research shows that over a 4-year period use of the drug in individuals age 65 and older increased by 75%. Joseph J. Palamar, PhD, MPH This population is especially vulnerable to potential adverse effects from cannabis and so this population needs to understand the potential risks associated with marijuana use, study investigator Joseph J. Palamar, PhD, MPH, associate professor, Department of Population Health, New York University (NYU) Langone Medical Center, New York City, told Medscape Medical News. The findings, he added, indicate a need for more [...]
Lire la suiteAssociation of Depression, Anxiety, and Trauma With Cannabis Use During Pregnancy Kelly C. Young-Wolff, PhD, MPH; Varada Sarovar, PhD; Lue-Yen Tucker, BA; Nancy C. Goler, MD; Stacey E. Alexeeff, PhD; Kathryn K. Ridout,MD, PhD; Lyndsay A. Avalos, PhD JAMA Network Open, 2020, 3, (2), e1921333. doi : 10.1001/jamanetworkopen.2019.21333 Introduction Prenatal cannabis use is increasing,1,2 and several qualitative studies3,4 indicate that pregnantwomen self-report using cannabis to manage stress and mood. However, few epidemiological studies have examined whether pregnant women with mental health disorders and trauma are at increased risk of using cannabis during pregnancy. Data from the Kaiser Permanente Northern California (KPNC) large integrated health care [...]
Lire la suiteHarmful Effects of Smoking Cannabis : A Cerebrovascular and Neurological Perspective Sabrina Rahman Archie and Luca Cucullo Frontiers in Pharmacology, 2019, 10, Article 1481. doi : 10.3389/fphar.2019.01481 Apart from being used as a medicine, cannabis or marijuana is the most widely abused recreational drug all over the world. The legalization and decriminalization of cannabis in Canada and various states of USA may be the underlying reason of the widespread popularity of it among young population. Various studies have reported about the relationship between cannabis use and different detrimental effects like cardiovascular, cerebrovascular, and neurological complications among different age groups. Specifically, the young population is [...]
Lire la suite