Chemical and Morphological Phenotypes in Breeding of Cannabis sativa L. Gianpaolo Grassi and John M. McPartland in S. Chandra et al. (eds.), Cannabis sativa L. - Botany and Biotechnology, Chapter 6, 2017, 137-160. Doi : 10.1007/978-3-319-54564-6_6 Abstract This chapter has two parts. The first part details five characters that contribute to phenotypic diversity in Cannabis. Cannabinoids can be assayed by quantity (dry weight percentage of cannabinoids in harvested material) or by quality (the THC/CBD ratio, or chemotype). Cannabinoid quality is largely genetic, possibly monogenic. We dissect the monogenic inheritance model (two alleles at a single gene locus). Essential oil is composed of volatile, aromatic terpenoids. [...]
Lire la suiteThe Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis: No “Strain,” No Gain Ethan B. Russo Frontiers in Plant Science, 2019, Volume 9, Article 1969, 1-8. Doi : 10.3389/fpls.2018.01969 The topic of Cannabis curries controversy in every sphere of influence, whether politics, pharmacology, applied therapeutics or even botanical taxonomy. Debate as to the speciation of Cannabis, or a lack thereof, has swirled for more than 250 years. Because all Cannabis types are eminently capable of cross-breeding to produce fertile progeny, it is unlikely that any clear winner will emerge between the “lumpers” vs. “splitters” in this taxonomical debate. This is compounded [...]
Lire la suiteGenomic and Chemical Diversity in Cannabis Ryan C. Lyncha,e, Daniela Vergaraa, Silas Tittesa, Kristin Whitea, C. J. Schwartzb, Matthew J. Gibbsb, Travis C. Ruthenburgc,d, Kymron deCesarec, Donald P. Landc, and Nolan C. Kanea CRITICAL REVIEWS IN PLANT SCIENCES, 2016, VOL. 35, NOS. 5–6, 349–363 Doi : 10.1080/07352689.2016.1265363 ABSTRACT Plants of the Cannabis genus are the only prolific producers of phytocannabinoids, compounds that strongly interact with the evolutionarily ancient endocannabinoid receptors shared by most bilaterian taxa. For millennia, the plant has been cultivated not only for these compounds, but also for food, rope, paper, and clothing. Today, specialized varieties yielding high-quality textile fibers, nutritional seed oil, or high cannabinoid [...]
Lire la suiteCannabis : From Cultivar to Chemovar II—A Metabolomics. Approach to Cannabis Classification Arno Hazekamp, Katerina Tejkalova, and Stelios Papadimitriou Cannabis and Cannabinoid Research, 2016, Volume 1, (1) Doi : 10.1089/can.2016.0017 Abstract Introduction : There is a large disparity between the ‘‘cultural’’ language used by patients using cannabis for selfmedication and the ‘‘chemical’’ language applied by scientists to get a deeper understanding of cannabis effects in laboratory and clinical studies. The distinction between Sativa and Indica types of cannabis, and the different biological effects associated with them, is a major example of this. Despite the widespread use of cannabis by selfmedicating patients, scientific studies are yet [...]
Lire la suiteThat which we call Indica, by any other name would smell as sweet. An essay on the history of the term Indica and the taxonomical conflict between the monotypic and polytypic views of Cannabis Jacob L. Erkelens, Arno Hazekamp Bedrocan BV, The Netherlands Cannabinoids, 2014, 9, (1), 9-15. What’s in a name ? An interesting feature of the worldwide subculture devoted to cannabis is the endless number of names given to its preparations (marijuana, pot, weed, kiff, bhang..). On top of that, there is a continuously grow-ing list of names used to describe different varieties and strains of the cannabis plant. As a result of [...]
Lire la suiteCannabis sativa L. CANNABACEAE Rainer W. Bussmann, Ketevan Batsatsashvili, Zaal Kikvidze, Narel Y. Paniagua-Zambrana, Manana Khutsishvili, Inesa Maisaia, Shalva Sikharulidze, and David Tchelidze © Springer Nature Switzerland AG 2020 in K. Batsatsashvili et al. (eds.), Ethnobotany of the Mountain Regions of Far Eastern Europe, Ethnobotany of Mountain Regions, doi : 10.1007/978-3-030-28940-9_33 Synonyms : Cannabis sativa L., Cannabis chinense Delile, Cannabis indica Lam, Cannabis sativa var. indica (Lam.) E. Small & Cronquist R. Local Names : Georgian : კანაფი (k’anapi); ქან (qan) (Grossheim 1952; Ketskhoveli et al. 1971–2011; Makashvili 1991; Fedorov 1984); English : Cannabis Botany and Ecology Annual; stems 50–150 cm, covered with appressed hairs; leaves long petioled, [...]
Lire la suiteDo medical cannabis growers attempt to produce cannabis with different cannabinoid concentrations than recreational growers? Sharon R. Sznitman, Monica J. Barratt, Tom Decorte, Pekka Hakkarainen, Simon Lenton, Gary Potter, Bernd Werse and Chris Wilkins Drugs and Alcohol Today, 2019, 19, (4), 251-256, Doi : 10.1108/DAT-06-2019-0021 Abstract Purpose – It is conceivable that cannabis cultivators who grow for medical purposes aim to improve the therapeutic index of their cannabis by attempting to produce particular concentrations of CBD and/or THC. The purpose of this paper is to examine whether small-scalemedical cannabis growers differ fromthose growing for recreational reasons in terms of self-assessed concentrations of THC and CBD [...]
Lire la suiteDeveloping Robust Standardised Analytical Procedures for Cannabinoid Quantification : Laying the Foundations for an Emerging Cannabis-Based Pharmaceutical Industry Matthew T. Welling, Lei Liu, Arno Hazekamp, Ashley Dowell, Graham J. King Medical Cannabis & Cannabinoids, 2019, 2, 1–13 Doi : 10.1159/000496868 Abstract The plant genus Cannabis is a prolific producer of unique pharmaceutically relevant metabolites, commonly referred to as cannabinoids. Robust and standardised methods for the quantification of cannabinoids within botanical and drug forms is a critical step forward for an emerging Cannabis- based pharmaceutical industry, which is poised for rapid expansion. Despite a growing body of analytical methods for the quantification of cannabinoids, few have [...]
Lire la suiteThe 2nd International Annual Congress on Controversies on Cannabis-Based Medicines (Med-Cannabis 2019) Barcelona, Spain, May 23–24, 2019 Abstracts Congress Chairs: Prof. Dr. Med. Winfried Häuser, Klinikum Saarbrücken, Germany Dr. Silviu Brill, Tel Aviv Medical Center, Israel Medical Cannabis & Cannabinoids, 2019, 2, 69–83 Published online: May 13, 2019 Doi : 10.1159/000500623 KRAGER : Basel · Freiburg · Paris · London · New York · Chennai · New Delhi · Bangkok · Beijing · Shanghai · Tokyo · Kuala Lumpur · Singapore · Sydney © 2019 The Author(s) Published by S. Karger AG, Basel E-Mail karger@karger.com www.karger.com/mca P-01 Cannabis and Metals: Soils Need to be Controlled Yann Barguil , Laura Chiaradia Biochemistry and Toxicology Laboratory, Gaston Bourret Territorial Hospital [...]
Lire la suite4th International Medical Cannabis Conference (CannX 2019) Tel Aviv, Israel, September 9–10, 2019 Abstracts Scientific Committee Dr. Adi Aran Director of the Neuro-Pediatric Unit, Shaare Zedek Medical Center, Israel Prof. Gil Bar-Sela Head, Cancer Center, Emek Medical Center Afula, Israel Dr. Nirit Bernstein Principle Research Scientist, Plant Physiology and Nutrition Institute of Soil Water and Environmental Sciences, Volcani Center, Israel Prof. Lumir Hanus Chief Scientist, Lumir Lab, Associate Professor, Palacký University, Jerusalem Biotechnology Park, Hebrew University, Ein Kerem Campus, Senior Fellow, IEHP, Thomas Jefferson University, Philadelphia, USA, Professor Chaver and Research Fellow, Hebrew University (Ret.) Institute for Drug Research, School of Pharmacy, Faculty of Medicine, Hebrew University, Israel Dr. Shaul Lev-Ran, MHA Deputy Director, Lev Hasharon Medical Center [...]
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