Synthetic cannabinoids and potential cardiac arrhythmia risk : an important message for drug users Jules C. Hancox, Nicola J. Kalk and Graeme Henderson Therapeutic Advances in Drug Safety, 2020, 11, 1-4. Doi : 10.1177/2042098620913416 Δ9-Tetrahydrocannabinol, the psychoactive ingredient in cannabis, and synthetic cannabinoid receptor agonists (SCRAs) activate the CB1 receptor to produce their profound behavioural effects and are widely used as recreational drugs. There is growing evidence that SCRAs, commonly known by the street name Spice or K2 (though there are many others, see: http://www.emcdda.europa.eu/publications/drug-profiles/synthetic-cannabinoids) can produce detrimental cardiovascular effects.(1) Commonly observed cardiotoxic effects of SCRAs include tachycardia, chest pain and hypertension.(1) However, bradycardia and [...]
Lire la suiteMarijuana Use Linked to Stroke, Arrhythmia in Young People Sue Hughes Medscape - Nov 12, 2019 https://www.medscape.com/viewarticle/921116?nlid=132614_2052&src=WNL_mdplsnews_191115_mscpedit_psyc&uac=292598PZ&spon=12&impID=2168195&faf=1019 Use of marijuana is linked to a higher risk of stroke and hospitalization for cardiac arrhythmia in young people, two new studies suggest. Both studies will be presented at this weekend's American Heart Association (AHA) Scientific Sessions 2019 in Philadelphia. In the observational stroke study, young adults with recent marijuana use had almost twice the risk compared with non-users of having had a stroke, and the risk increased further among frequent marijuana users. The risk of having had a stroke was even higher — three times that of non-users — in frequent [...]
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