A cross-sectional examination of choice and behavior of veterans with access to free medicinal cannabis Mallory J E Loflin, Kimberly Babson, James Sottile, Sonya B Norman, Staci Gruber, and Marcel O Bonn-Miller The American Journal of Drug and Alcohol Abuse, 2019, VOL. 45, NO. 5, 506–513. Doi : 10.1080/00952990.2019.1604722 ABSTRACT Background : With a rise in public pressure to increase veteran access to medicinal cannabis, free cannabis collectives for military veterans are proliferating across the US. Objectives : The aim of the current study was to document which cannabis formulations and routes of administration are chosen by veterans with increased access to cannabis, and to determine [...]
Lire la suiteUnique treatment potential of cannabidiol for the prevention of relapse to drug use: preclinical proof of principle Gustavo Gonzalez-Cuevas, Remi Martin-Fardon, Tony M. Kerr, David G. Stouffer, Loren H. Parsons, Dana C. Hammell, Stan L. Banks, Audra L. Stinchcomb and Friedbert Weiss Neuropsychopharmacology, 2018, 43, 2036–2045. Doi : 10.1038/s41386-018-0050-8 Cannabidiol (CBD), the major non-psychoactive constituent of Cannabis sativa, has received attention for therapeutic potential in treating neurologic and psychiatric disorders. Recently, CBD has also been explored for potential in treating drug addiction. Substance use disorders are chronically relapsing conditions and relapse risk persists for multiple reasons including craving induced by drug contexts, susceptibility to [...]
Lire la suitePerceived outcomes of psychedelic microdosing as self-managed therapies for mental and substance use disorders Toby Lea & Nicole Amada & Henrik Jungaberle & Henrike Schecke & Norbert Scherbaum & Michael Klein Psychopharmacology, 2020. Di : 10.1007/s00213-020-05477-0 Abstract Rationale : The regular consumption of very small doses of psychedelic drugs (known as microdosing) has been a source of growing media and community attention in recent years. However, there is currently limited clinical and social research evidence on the potential role of microdosing as therapies for mental and substance use disorders. Objectives : This paper examined subjective experiences of microdosing psychedelics to improve mental health or to cease [...]
Lire la suitePersisting Reductions in Cannabis, Opioid, and Stimulant Misuse After Naturalistic psychedelic Use : An Online Survey Albert Garcia-Romeu, Alan K. Davis, Earth Erowid, Fire Erowid, Roland R. Griffiths and Matthew W. Johnson Frontiers in Psychiatry, 2020, Vol 10, Article 955. Doi : 10.3389/fpsyt.2019.00955 Background : Observational data and preliminary studies suggest serotonin 2A agonist psychedelics may hold potential in treating a variety of substance use disorders (SUDs), including opioid use disorder (OUD). Aims : The study aim was to describe and analyze self-reported cases in which naturalistic psychedelic use was followed by cessation or reduction in other substance use. Methods : An anonymous online survey of [...]
Lire la suiteL’invité de 6h20 – La médecine psychédélique renaît peu à peu Fév15 Revue de presse vendredi 14 février 2020 par Mathilde Munos Stéphanie Chayet, journaliste, auteure de Phantastica, ces substances interdites qui guérissent (Grasset) Stéphanie Chayet : “Il n’y a pas plus de troubles psychiatriques chez les usagers de drogues psychédéliques Après le cannabis thérapeutique, verra-t-on d’autres substances, aujourd’hui considérées comme des drogues, devenir des médicaments ? , nous en parlons avec la journaliste Stéphanie Chayet, auteure de « Phantastica ». Elle est l’invitée du 5/7. https://www.circ-asso.net/linvite-de-6h20-la-medecine-psychedelique-renait-peu-a-peu/ Lecteur audio 00:00 00:00 Source : franceinter.fr Catégorie Revue de presse 15 février 2020
Lire la suitePsilocybin-Assisted Therapy : A Review of a Novel Treatment for Psychiatric Disorders Kelan Thomas, Pharm.D., M.S., Benjamin Malcolm, Pharm.D., M.P.H., and Dan Lastra, B.S. Journal of Psychoactive Drugs, 2017 Doi : 10.1080/02791072.2017.1320734 Abstract Recent research suggests that functional connectivity changes may be involved in the pathophysiology of psychiatric disorders. Hyperconnectivity in the default mode network has been associated with psycho-pathology, but psychedelic serotonin agonists like psilocybin may profoundly disrupt these dysfunctional neural network circuits and provide a novel treatment for psychiatric disorders. We have reviewed the current literature to investigate the efficacy and safety of psilocybin-assisted therapy for the treatment of psychiatric disorders. There were [...]
Lire la suiteQue (Devrait-on) Savoir sur la Pharmacologie du Cannabidiol ? Article rédigé par les Centres d’Addictovigilance de Grenoble, Marseille, Paris Addictovigilance, Bulletin de l’Association des Centres d’Addictovigilance, 2020, 13. www.addictovigilance.fr Messages clefs Les phyto-cannabinoïdes et les cannabinoïdes de synthèse ont des effets très variés,utiles à caractériser d’un point devue pharmacologique pour mieux préciser les effets de chacun et leurs éventuelles interactions chez l’Homme, a fortiori dans un contexte de large diffusion. Le cannabidiol (CBD) est l’un des principaux phyto-cannabinoïdes présent dans Cannabis sativa, avec le tétrahydrocannabinol (THC). Le CBD a une action pléiotropique notamment sur les récepteurs à la sérotonine, à la dopamine et pas ou très peu [...]
Lire la suite“Go Ask Alice”: The Case for Researching Schedule I Drugs Kenneth V. ISERSON Cambridge Quarterly of Healthcare Ethics, 2019, 28, 168–177. © Cambridge University Press 2018. doi : 10.1017/S0963180118000518 Abstract : The available treatments for disorders affecting large segments of the population are often costly, complex, and only marginally effective, and many have numerous side effects. These disorders include dementias, debilitating neurological disorders, the multiple types of drug addiction, and the spectrum of mental health disorders. Preliminary studies have shown that a variety of psychedelic and similar U.S. Drug Enforcement Administration Schedule I drugs may offer better treatment options than those that currently exist and pose potentially [...]
Lire la suiteExploring ayahuasca-assisted therapy for addiction: A qualitative analysis of preliminary findings among an Indigenous community in Canada Elena ARGENTO, Rielle CAPLER, Gerald THOMAS, Philippe LUCAS & Kenneth W. TUPPER Drug and Alcohol Review, 2019 Doi : 10.1111/dar.12985 Abstract Introduction and Aims. A previous observational study of ayahuasca-assisted therapy demonstrated statistically significant reductions in self-reported problematic cocaine use among members of an Indigenous community in Canada. This paper aims to qualitatively explore the impact of ayahuasca assisted therapy on addiction and other substance use-related outcomes and elucidate the lived experiences of participants. Design and Methods. Qualitative interviews were conducted with 11 adult Indigenous participants of the ayahuasca-assisted [...]
Lire la suiteCannabis : saurez-vous bien faire la distinction entre le «bien-être» et la «récréation» ? Jean-Yves NAU Blog Le Monde, 23 décembre 2019 Bonjour Est-ce une nouvelle tentative pour dépénaliser/légaliser une substance illicite mais très largement consommée ? L’Assemblée nationale vient de créér une « Mission d’information commune sur la réglementation et l’impact des différents usages du cannabis ». Une mission composée de trente-trois députés et issue des réflexions de … six commissions (affaires économiques, affaires sociales, lois, finances, affaires culturelles et éducatives, développement durable). Pourquoi développer une telle énergie législative ? Parce qu’ « en France la réglementation des usages du cannabis a particulièrement évolué ces dix dernières années » [il s’agit de [...]
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