« Les associations Principes Actifs et PsychoActif, en lien avec l’équipe de recherche du SESSTIM, réalisent une enquête sur le cannabis comme méthode de substitution aux autres drogues. https://www.principesactifs.org/enquete-cannabris/ Certains consommateurs de drogues ont fait le choix d’utiliser le cannabis pour réduire leurs consommations, aider au sevrage ou maintenir un traitement de substitution aux opiacés. Nous cherchons à décrire ces pratiques encore peu connues du monde médical et les bénéfices perçus par les usagers. Si vous êtes concerné(e), racontez-nous votre expérience via ce questionnaire et aidez-nous à montrer la réalité de ces pratiques ! Cette enquête est anonyme et prendra environ 15 minutes de votre [...]
Lire la suiteACM-Bulletin du 04 Octobre 2021 Afrique du Sud: Un premier patient est officiellement autorisé à consommer du cannabis pour soulager ses douleurs Science/Homme: Le cannabis peut être bénéfique dans le prurit neuropathique de la sclérose latérale amyotrophique selon un rapport de cas Science/Homme: Le cannabis peut améliorer la douleur et le sommeil dans la fibromyalgie Science/Homme: De nombreuses femmes utilisent le cannabis pour atténuer les symptômes de la ménopause En bref Un coup d'�il sur le passé Afrique du Sud: Un premier patient est officiellement autorisé à consommer du cannabis pour soulager [...]
Lire la suiteShort and Long-Term Effects of Cannabis on Symptoms of Post-Traumatic Stress Disorder Emily M. LaFrance, Nicholas C. Glodosky, Marcel Bonn-Miller, Carrie Cuttler Journal of Affective Disorders, 2020, 274, 298–304 Doi : 10.1016/j.jad.2020.05.132 A B S T R A C T Background : Many individuals use cannabis to manage symptoms of post-traumatic stress disorder (PTSD), and evidence indicates that the endocannabinoid system represents a viable target for treating these symptoms. Method : Data from 404 medical cannabis users who self-identified as having PTSD were obtained from Strainprint®, a medical cannabis app that patients use to track changes in symptoms as a function of different strains and doses [...]
Lire la suiteStudy finds no evidence marijuana use increases stroke risk HealthDay News, 2020. https://www.upi.com/Health_News/2020/06/04/Study-finds-no-evidence-marijuana-use-increases-stroke-risk/3321591274273/?upi_ss=Cannabis An observational study conducted at hospitals found no evidence that marijuana use increases risk for stroke. File Photo by Atomazul/Shutterstock Whether pot use increases the risk of stroke has been hotly debated, and now a new study adds to evidence that it doesn't. "Our observational study looked specifically at recent cannabis use by reviewing drug testing data for people admitted to the hospital. While more research is needed with larger numbers of people, our study lends support to the studies showing that cannabis use does not increase the risk of stroke," said [...]
Lire la suiteTRIBUNE Cannabis, la France en descente Jean-Marc Pasquet, Haut fonctionnaire, président du think tank Novo Ideo Libération, 19 aout 2021 https://www.liberation.fr/idees-et-debats/tribunes/cannabis-la-france-en-descente-20210819_SU237TGQKRGXTCRUK6KMQTD3UM/ Record de consommateurs ? Contrairement au modèle portugais qui envisage l’usager comme un patient, le système français privilégie une politique pénale. Les Lusitaniens obtiennent pourtant de bien meilleurs résultats en termes de consommation et de prévalence. A Paris en 9 janvier 2019. (Cyril Zannettacci/Vu pour Libération) Notre pays détient le record de la proportion d’usagers de drogues illicites au sein de l’UE, et celui en particulier des 15 à 34 ans. 80 % de la consommation est liée au cannabis. Elle concerne cinq millions d’usagers dans l’année, [...]
Lire la suiteEfficacy and Safety of Cannabidiol Plus Standard Care vs Standard Care Alone for the Treatment of Emotional Exhaustion and Burnout Among Frontline Health CareWorkers During the COVID-19 Pandemic. A Randomized Clinical Trial José Alexandre S. Crippa, PhD; AntonioW. Zuardi, PhD; Francisco S. Guimarães, PhD; Alline Cristina Campos, PhD; Flávia de Lima Osório, PhD; Sonia Regina Loureiro, PhD; Rafael G. dos Santos, PhD; José Diogo S. Souza, MD; Juliana Mayumi Ushirohira, MD, MSc; Julia Cozar Pacheco, RPh; Rafael Rinaldi Ferreira, PhD, RPh; Karla Cristinne Mancini Costa, MSc; Davi Silveira Scomparin, MSc; Franciele Franco Scarante, MSc; Isabela Pires-Dos-Santos, VMD; Raphael Mechoulam, PhD; Flávio Kapczinski, PhD; Benedito [...]
Lire la suiteCannabinoid-based Medications for Pain Raymond M. St. Marie, MD; Raphael J. Leo, MA, MD Current Psychiatry, 2021, 20(5), 21-33. Abstract and Introduction Introduction Against the backdrop of an increasing opioid use epidemic and a marked acceleration of prescription opioid–related deaths,[1,2] there has been an impetus to explore the usefulness of alternative and co-analgesic agents to assist patients with chronic pain. Preclinical studies employing animal-based models of human pain syndromes have demonstrated that cannabis and chemicals derived from cannabis extracts may mitigate several pain conditions.[3] Because there are significant comorbidities between psychiatric disorders and chronic pain, psychiatrists are likely to care for patients with chronic pain. As [...]
Lire la suiteNeuroprotective Effect of Cannabidiol Against Hydrogen Peroxide in Hippocampal Neuron Culture Jungnam Kim, Ji Yu Choi, Jeongyeon Seo, and Insung S. Choi Cannabis and Cannabinoid Research, 2021, Volume 6, Number 1, 40-48. Doi : 10.1089/can.2019.0102 Abstract Introduction : Reports on the neurotoxic and neuroprotective effects of cannabidiol (CBD) have not been in complete accord, showing different and somewhat contradictory results depending upon the brain cell types and experimental conditions employed. This work systematically examines the neuroprotective capability of CBD against oxidative stress (i.e., hydrogen peroxide [H2O2]) as well as its toxicity profile in the in vitro culture platform of primary hippocampal neurons. Materials and Methods : [...]
Lire la suiteReducing Effect of Cannabidiol on Alcohol Self-Administration in Sardinian Alcohol-Preferring Rats Paola Maccioni, Jessica Bratzu, Mauro A.M. Carai, Giancarlo Colombo, and Gian Luigi Gessa Cannabis and Cannabinoid Research, 2021, Doi : 10.1089/can.2020.0132 Abstract Introduction : Cannabidiol (CBD) is a major cannabinoid extracted from Cannabis sativa with no abuse potential. Data from recent rodent studies suggest that amelioration of alcohol-motivated behaviors may be one of the numerous pharmacological effects of CBD. This study was designed to contribute to this research, assessing the effect of CBD on operant oral alcohol self-administration in selectively bred Sardinian alcohol preferring (sP) rats, a validated animal model of excessive alcohol consumption. [...]
Lire la suiteCannabinoids, Phenolics, Terpenes and Alkaloids of Cannabis Mohamed M. Radwan, Suman Chandra, Shahbaz Gul and Mahmoud A. ElSohly Molecules, 2021, 26, 2774. Doi : 10.3390/molecules26092774 Abstract : Cannabis sativa is one of the oldest medicinal plants in the world. It was introduced into western medicine during the early 19th century. It contains a complex mixture of secondary metabolites, including cannabinoids and non-cannabinoid-type constituents. More than 500 compounds have been reported from C. sativa, of which 125 cannabinoids have been isolated and/or identified as cannabinoids. Cannabinoids are C21 terpeno phenolic compounds specific to Cannabis. The non-cannabinoid constituents include: non-cannabinoid phenols, flavonoids, terpenes, alkaloids and others. This review discusses [...]
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