Therapeutic Satisfaction and Subjective Effects of Different Strains of Pharmaceutical-Grade Cannabis Tibor M. Brunt, Marianne van Genugten, Kathrin Honer-Snoeken, Marco J. van de Velde, and Raymond J.M. Niesink Journal of Clinical Psychopharmacoly, 2014, 34, 344Y349 Doi : 10.1097/JCP.0000000000000129 Abstract : In The Netherlands, pharmaceutical-grade cultivated cannabis is distributed for medicinal purposes as commissioned by the Ministry of Health. Few studies have thus far described its therapeutic efficacy or subjective (adverse) effects in patients. The aims of this study are to assess the therapeutic satisfaction within a group of patients using prescribed pharmaceutical-grade cannabis and to compare the subjective effects among the available strains with special [...]
Lire la suiteAcute and chronic effects of cannabinoids on effort-related decision-making and reward learning: an evaluation of the cannabis ‘amotivational’ hypotheses Will Lawn, Tom P. Freeman, Rebecca A. Pope, Alyssa Joye, Lisa Harvey, Chandni Hindocha, Claire Mokrysz, Abigail Moss, Matthew B. Wall, Michael A.P. Bloomfield, Ravi K. Das, Celia J.A. Morgan, David J. Nutt, H. Valerie Curran Psychopharmacology, 2016, 233, 3537–3552 Doi : 10.1007/s00213-016-4383-x Abstract Rationale : Anecdotally, both acute and chronic cannabis use have been associated with apathy, amotivation, and other reward processing deficits. To date, empirical support for these effects is limited, and no previous studies have assessed both acute effects of Δ-9-tetrahydrocannabinol (THC) and [...]
Lire la suiteCanada : La consommation de cannabis des 15-17 ans a baissé de 47% depuis la légalisation Newsweed, 20 février 2020 Par Aurélien BERNARD Depuis la légalisation du cannabis au Canada en octobre 2018, Statistique Canada, l’organe statistique national, conduit tous les 3 mois une enquête pour récolter des données sur la consommation de cannabis des Canadiens. Malgré les limites inhérentes au déclaratif, ces données permettent d’entrevoir les effets de la légalisation sur les Canadiens. Consommation de cannabis selon l’âge Ainsi, après un an de légalisation, plus de 5,1 millions de Canadiens de 15 ans ou plus ont déclaré avoir consommé du cannabis en 2019 au cours [...]
Lire la suiteThe Psychiatric Consequences of Cannabinoids Joao P. De Aquino, Mohamed Sherif, Rajiv Radhakrishnan, John D. Cahill, Mohini Ranganathan and Deepak C. D’Souza Clinical Therapeutics, 2018, 40, (9), 14481456 Doi : 10.1016/j.clinthera.2018.03.013 ABSTRACT With rising rates of cannabis use in the general population and an increasing number of US states legalizing both recreational and medical cannabis use, it is important to be informed about the adverse consequences of cannabinoids. This Commentary provides an overview of the psychiatric effects of plant-based and synthetic cannabinoids, differentiating acute effects from effects associated with persistent use. Cannabinoids produce multiphasic and dose dependent effects on anxiety, mood, and perception, in addition [...]
Lire la suiteCannabis in Chinese Medicine : Are Some Traditional Indications Referenced in Ancient Literature Related to Cannabinoids? E. Joseph Brand and Zhongzhen Zhao Frontiers in Pharmacology, 2017, vol 8, Article 108, 1-11. doi : 10.3389/fphar.2017.00108 Cannabis sativa L. (Cannabaceae) has a long history of utilization as a fiber and seed crop in China, and its achenes (“seeds”) as well as other plant parts have been recorded in Chinese medical texts for nearly 2000 years. While the primary applications of cannabis in Chinese medicine center around the use of the achenes, ancient indications for the female inflorescence, and other plant parts include conditions such as pain [...]
Lire la suiteIACM-Bulletin du 14 Février 2020 Science/Animal: Le cannabigerol est efficace contre les infections par des bactéries résistantes aux antibiotiques Economy/Écologie: Données sur la quantité d'électricité consommée par l'industrie du cannabis Science/Homme: Environ la moitié des patients souffrant de lombalgie ont pu arrêter toute consommation d'opioïdes après avoir commencé la consommation de cannabis Europe/ONU: La Commission Européenne propose un vote unifié de l'UE sur la programmation de l’OMS sur le cannabis Science/Homme: De nombreux patients atteints d'arthrite consomment du cannabis Science/Homme: Le cannabis peut être utile contre l'insomnie chez les personnes âgées souffrant de douleur [...]
Lire la suiteLongitudinal Changes in Cognition in Young Adult Cannabis Users Mary Becker, Paul F. Collins, Ashley Schultz, Snežana Urošević, Brittany Schmaling, and Monica Luciana The Journal of Clinical and Experimental Neuropsychology, 2018, 40, (6), 529–543. doi : 10.1080/13803395.2017.1385729 Abstract Introduction : Adolescent cannabis use (CU) is associated with impaired attention, executive function, and verbal learning/memory. These associations are generally observed in cross-sectional studies. Longitudinal studies of cannabis users are lacking. Method : The present study examines associations between CU and cognition over time in chronic daily adolescent-onset CUs, as compared to non-using controls. Both groups completed a neuropsychological battery at study intake and again two years later. Results [...]
Lire la suiteInvestigation of Sex-Dependent Effects of Cannabis in Daily Cannabis Smokers Ziva D. Cooper and Margaret Haney Drug & Alcohol Dependence, 2014 March 1, 136, 85–91. doi :10.1016/j.drugalcdep.2013.12.013 Abstract Background—Women exhibit an accelerated progression from first cannabis use to cannabis use disorder (CUD) and show pronounced negative clinical issues related to CUD relative to men. Whether sex-dependent differences in cannabis’ direct effects contribute to the heightened risk in women is unknown. This analysis directly compared cannabis’ abuse-related subjective effects in men and women matched for current cannabis use. Methods—Data from four double-blind, within-subject studies measuring the effects of active cannabis (3.27–5.50% THC, depending on study) relative to [...]
Lire la suiteRisk of Persistence and Progression of Use of 5 Cannabis Products After Experimentation Among Adolescents Jessica L. Barrington-Trimis, PhD; Junhan Cho, PhD; Esthelle Ewusi-Boisvert, BA; Deborah Hasin, PhD; Jennifer B. Unger, PhD; Richard A. Miech, PhD; Adam M. Leventhal, PhD JAMA Network Open, 2020, 3, (1), e1919792. doi : 10.1001/jamanetworkopen.2019.19792 Abstract IMPORTANCE : While a diverse array of cannabis products that may appeal to youth is currently available, it is unknown whether the risk of persistent cannabis use and progression to higher frequency of use after experimentation differs among cannabis products. OBJECTIVE : To estimate the comparative relative risk of experimental use of 5 cannabis products [...]
Lire la suiteThe health and social effects of nonmedical cannabis use World Health Organization, 2016. CONTENTS Foreward. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . v Acknowledgements .. . . . . . . . . . . . . . . . . . . [...]
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