Marijuana for Symptoms of PTSD in U.S. Veterans Category: MAPS-Sponsored Medical Marijuana Research https://maps.org/research/mmj/marijuana-us/ Placebo-Controlled, Triple-Blind, Randomized Crossover Pilot Study of the Safety and Efficacy of Four Different Potencies of Smoked Marijuana in 76 Veterans with Chronic, Treatment-Resistant Posttraumatic Stress Disorder (PTSD) Site Principal Investigator: Sue Sisley, M.D. Coordinating Principal Investigator: Marcel Bonn-Miller, Ph.D. Co-Investigator: Paula Riggs, M.D. This study has completed enrollment. This study will explore whether smoked marijuana can help reduce PTSD symptoms in 76 U.S. veterans with chronic, treatment-resistant posttraumatic stress disorder (PTSD). Participants must be U.S. veterans, men or women, aged 18 or older with a diagnosis of PTSD that has not improved after [...]
Lire la suiteMedical Marijuana MAPS has completed the first-ever clinical trial of smoked marijuana for symptoms of posttraumatic stress disorder (PTSD) in veterans of war. https://maps.org/research/mmj MAPS is working to demonstrate the safety and efficacy of smoked botanical marijuana as a prescription medicine for specific medical uses to the satisfaction of the U.S. Food and Drug Administration. Our efforts to initiate medical marijuana research have been hindered by the National Institute on Drug Abuse (NIDA) and the Drug Enforcement Administration (DEA) since our founding in 1986. NIDA's previous monopoly on the supply of marijuana for research and the DEA's prior refusal to allow researchers to grow [...]
Lire la suiteUsing CBD to Tame a Cannabis High? Small Doses May Have the Opposite Effect Bailey Rahn, February 28, 2019, https://www.leafly.com Posted By Bailey Rahn On February 28, 2019 @ 3:52 pm In Science & Tech https://www.leafly.com/news/science-tech/how-cbd-dose-affects-cannabis-effects/print/ (imaginima/iStock) Take some CBD, they said. You’ll feel less high, they said. This common piece of advice fed to THC-shy consumers can effectively bring someone back down to earth. It works—sometimes. But new research shows there’s likely more nuance in the solution than we initially thought. Scientists found that a high dose of CBD dampened the effects of a THC high, but participants reported a stronger high when combined with low [...]
Lire la suiteLeafly : CBD in the Spotlight at SXSW, Despite Legal Gray Area Written by Tonyia Cone on March 26, 2019. Posted in MAPS in the Media Summary: A new article from Leafly reflects on the Cannabusiness session at South by South West (SXSW) 2019, where MAPS Policy and Advocacy Director Natalie Lyla Ginsberg, M.S.W., represented MAPS through participating in a panel discussion, The Future of Hemp and Health. Originally appearing here. A simple stroll across the festival grounds brought visitors past an array of CBD-focused booths: Kentucky-based MedTerra, for example, hosted a two-day, CBD-focused venue, dubbed “Wellhaus,” that featured a CBD infusion bar. [...]
Lire la suiteNo significant effect of cannabis use on the count and percentage of circulating CD4 T-cells in HIV-HCV co-infected patients (ANRS CO13-HEPAVIH French cohort) Fabienne MARCELLIN, Caroline LIONS, Eric ROSENTHAL, Perrine ROUX, Philippe SOGNI, Linda WITTKOP, Camelia PROTOPOPESCU, Bruno SPIRE, Dominique SALMON-CERON, François DABIS, Maria Patrizia CARRIERI, & HEPAVIH ANRS CO13 STUDY GROUP (10Paris Descartes University, Paris, France) Drug and Alcohol Review (2016) DOI: 10.1111/dar.12398 Abstract : Introduction and Aims. Despite cannabis use being very common in patients co-infected with HIV and hepatitis C virus (HCV), its effect on these patients’ immune systems remains undocumented. Documenting the potential effect of cannabis use on HIV immunological markers [...]
Lire la suiteAntidepressant-Like and Anxiolytic-Like Effects of Cannabidiol : A Chemical Compound of Cannabis sativa Alexandre R. de Mello Schier, Natalia P. de Oliveira Ribeiro, Danielle S. Coutinho, Sergio Machado, Oscar Arias-Carrión, José A. Crippa, Antonio W. Zuardi, Antonio E. Nardi and Adriana C. Silva CNS & Neurological Disorders - Drug Targets, 2014, 13, 953-960 Abstract : Anxiety and depression are pathologies that affect human beings in many aspects of life, including social life, productivity and health. Cannabidiol (CBD) is a constituent non-psychotomimetic of Cannabis sativa with great psychiatric potential, including uses as an antidepressant-like and anxiolytic-like compound. The aim of this study is to review [...]
Lire la suiteLe Chanvre (Cannabis Sativa), par booksofdante40 https://wp.me/p2SVqZ-1NL https://booksofdante.wordpress.com/2019/03/07/le-chanvre-cannabis-sativa/ Synonymes : chanevet, chanvret, canebier, cherve, chervet, chêne, chenove, etc. Le point de départ de l'histoire du chanvre se situe à mi-chemin entre la Turquie et la Chine, ce que l'on appellerait l'Asie centrale : cette zone d'origine comprend une partie de la Chine et du sous-continent indien, une portion iranienne et se compose enfin des ex républiques soviétiques que sont l'Ouzbékistan, le Turkménistan, l'Afghanistan, le Tadjikistan, le Kazakhstan et le Kirghizistan. A peu près. De là, il irradia tant vers la Chine orientale qu'en direction de l'ouest. En Chine, son usage médicinal remonte au moins au XV [...]
Lire la suiteEffects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder Charlotte Marie Pretzsch, Jan Freyberg, Bogdan Voinescu, David Lythgoe, Jamie Horder, Maria Andreina Mendez, Robert Wichers, Laura Ajram, Glynis Ivin, Martin Heasman, Richard A. E. Edden, Steven Williams, Declan G. M. Murphy, Eileen Daly and Gráinne M. McAlonan Neuropsychopharmacology, 2019, 0, 1–8; https://doi.org/10.1038/s41386-019-0333-8 Abstract : There is increasing interest in the use of cannabis and its major non-intoxicating component cannabidiol (CBD) as a treatment for mental health and neurodevelopmental disorders, such as autism spectrum disorder (ASD). However, before [...]
Lire la suiteAn Update of Current Cannabis-Based Pharmaceuticals in Pain Medicine Ivan Urits, Matthew Borchart, Morgan Hasegawa, Justin Kochanski, Vwaire Orhurhu, Omar Viswanath Pain and Therapy, 2019, https://link.springer.com/article/10.1007/s40122-019-0114-4 https://doi.org/10.6084/m9.figshare.7619327 ABSTRACT : Cannabis users have long reported therapeutic properties of the plant for a variety of conditions, some of which include nausea, emesis, seizures, cancer, neurogenic diseases and pain control. Research has elucidated many cannabinoid pharmacodynamic and pharmacokinetic properties, expanding the potential use of cannabinoids as a medical therapy. Due to the inconsistent delivery and control of the active components involved with smoking, pharmaceutical companies are investigating and prioritizing routes other than smoke inhalation for therapeutic use of cannabinoids. In [...]
Lire la suiteTherapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection. Evan C. Rosenberg, Pabitra H. Patra, and Benjamin J. Whalley Epilepsy & Behavior, 2017 May ; 70(Pt B), 319–327 PMID : 28190698 PMCID : PMC5651410 DOI : 10.1016/j.yebeh.2016.11.006 Abstract : The isolation and identification of the discrete plant cannabinoids in marijuana revived interest in analyzing historical therapeutic claims made for cannabis in clinical case studies and anecdotes. In particular, sources as old as the 11th and 15th centuries claimed efficacy for crude marijuana extracts in the treatment of convulsive disorders, prompting a particularly active area of preclinical research into [...]
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