High-Potency Cannabis Products Linked to Suicidality Doug Brunk Medscape Medical News © 2021 WebMD, LLC February 22, 2021 Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. In the days since recreational sales of marijuana became legal in Colorado in January 2014, concerning trends have emerged among the state's young cannabis users. Dr Paula Riggs According to a report from the Rocky Mountain High Intensity Drug Trafficking Area, between 2014 and 2017, the number of suicides positive for marijuana increased 250% among those aged 10-19 years (from 4 to 14) and 22% among those aged 20 and older (from 118 to 144). "Other states are seeing something [...]
Lire la suiteCannabis for Pain? An Expert's Guidance John Watson Medscape Neurology © 2021 WebMD, LLC January 05, 2021 Mark Steven Wallace, MD Many have put forth medical cannabis as a promising treatment for chronic pain that can potentially replace opioids. However, although it's never been easier for patients to access medical cannabis, those researching its use say that the structural challenges inherent to studying a Schedule 1 drug remain formidable. Medscape recently spoke with Mark Steven Wallace, MD, a pain management specialist and chair of the Division of Pain Medicine at UC San Diego Health, about the latest data on medical cannabis and the challenges in studying its clinical use in pain [...]
Lire la suiteOriginal Investigation | Substance Use and Addiction Association of Recreational Cannabis Legalization With Maternal Cannabis Use in the Preconception, Prenatal, and Postpartum Periods Kara R. Skelton, PhD; Amelie A. Hecht, PhD; Sara E. Benjamin-Neelon, PhD, JD JAMA Network Open, 2021, 4, (2), 1-12, e210138. doi : 10.1001/jamanetworkopen.2021.0138 Abstract IMPORTANCE : Recent studies have revealed increases in population-level cannabis use after legalization of recreational cannabis. However, the association of cannabis legalization with maternal cannabis use during important life stages remains unknown. OBJECTIVE : To investigate the association of legalization of recreational cannabis with maternal cannabis use during the preconception, prenatal, and postpartum periods. DESIGN, SETTING, AND PARTICIPANTS : This repeated [...]
Lire la suitePro-psychotic effects of synthetic cannabinoids: interactions with central dopamine, serotonin and glutamate systems William E. Fantegrossi, Cathryn D. Wilson, and Michael D. Berquist III Drug Metabolism Reviews, 2018, 50, (1), 65–73. doi : 10.1080/03602532.2018.1428343 Abstract An association between marijuana use and schizophrenia has been noted for decades, and the recent emergence of high-efficacy synthetic cannabinoids (SCBs) as drugs of abuse has lead to a growing number of clinical reports of persistent psychotic effects in users of these substances. The mechanisms underlying SCB-elicited pro-psychotic effects is unknown, but given the ubiquitous neuromodulatory functions of the endocannabinoid system, it seems likely that agonist actions at cannabinoid type-1 [...]
Lire la suiteLa folie du Cannabis. Entre non-sens et préjudice, Mischa Hauswirth, Editions Solanacée, 2020, https://edition-solanacee.us7.list-manage.com/track/click?u=84b6c6a0effdaca8f68d4d1e0&id=c04d113cce&e=eaf78900b6 Préface : Dr Christian Sueur, psychiatre, Praticien Hospitalier, président du GRECC. C’est avec beaucoup d’enthousiasme que j’ai accepté d’écrire une préface pour cet excellent livre de Mischa Hauswirth, qui renouvelle, par sa clarté, sa rigueur, et son « encyclopédisme », l’ouvrage de Lynn Zimmer et John P. Morgan, « Marijuana, mythes et réalités », édité il y a déjà 20 ans (1997 pour l’édition originale, et 2000, pour la traduction française). Comme cet ouvrage « historique », le livre de Mischa Hauswirth rassemble tous les éléments utiles à la compréhension du « phénomène cannabis », tant sur le plan historique [...]
Lire la suiteLe Cannabis en France au xix e siècle : une histoire médicale. Jacques ARVEILLER L’Évolution Psychiatrique, 2013, 78, (3), Doi : 10.1016/j.evopsy.2013.06.004 Résumé Ce texte se propose de retracer l’histoire du Cannabis (haschich) dans la France du xixe siècle. Dans un premier temps est rappelé l’état des connaissances concernant le cannabis au début du xixe siècle. Sont distingués les origines géographiques et les trajets qu’empruntent ces connaissances à partir de l’Inde, du Proche-Orient et du Maghreb, jusqu’au milieu du xixe siècle. On se centre ensuite sur l’œuvre de l’aliéniste Joseph Moreau de Tours (1804–1884), ainsi que celle de ses prédécesseurs français comme Alexandre Brierre de [...]
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