Therapeutic Use of LSD in Psychiatry : A Systematic Review of Randomized-Controlled Clinical Trials Juan José Fuentes, Francina Fonseca, Matilde Elices, Magí Farré and Marta Torrens Frontiers in Psychiatry, 2020, Vol 10, Article 943. doi : 10.3389/fpsyt.2019.00943 Lysergic acid diethylamide (LSD) was studied from the 1950s to the 1970s to evaluate behavioral and personality changes, as well as remission of psychiatric symptoms in various disorders. LSD was used in the treatment of anxiety, depression, psychosomatic diseases and addiction. However, most of the studies were not performed under contemporary standards, and it has taken several decades for a resurgence of interest in LSD research and [...]
Lire la suiteTherapeutic Potential of Psychedelic Drugs Justin Briglio University of Maine, 2015, 31 p. Table of Contents Introduction......................................................................................................................................3 History of Psychedelic Research.....................................................................................................6 Recent Research...............................................................................................................................8 Neurobiology of Psychedelics.........................................................................................................9 Therapeutic Potential of Psilocybin...............................................................................................12 Therapeutic Potential of LSD........................................................................................................15 Therapeutic Potential of Ayahuasca..............................................................................................19 Therapeutic Potential of Ibogaine..................................................................................................22 Conclusion.....................................................................................................................................26 References......................................................................................................................................28 A psychedelic compound is a psychoactive drug whose main action is to alter perception and cognition. Psychedelics are distinctive from other psychoactive drugs in that they alter the mind, whereas opiates or stimulants alter the mood (Meyer & Quenzer, 2013). Psychedelics affect nature of consciousness itself and access otherwise unknown states of consciousness, as opposed to affecting the degree or extent of one's consciousness and inducing proverbial moods such as [...]
Lire la suiteIs there a role for cannabidiol in psychiatry ? Julia Machado Khoury , Maila de Castro Lourenço das Neves, Marco Antônio Valente Roque, Daniela Alves de Brito Queiroz , Andre Augusto Corrêa de Freitas, Angelo de Fatima, Fabrıcio Moreira and Frederico Duarte Garcia The World Journal of Biological Psychiatry, 2017, 16 p. Doi : 10.1080/15622975.2017.1285049 ABSTRACT Objectives : Understanding whether cannabidiol (CBD) is useful and safe for the treatment of psychiatric disorders is essential to empower psychiatrists and patients to take good clinical decisions. Our aim was to conduct a systematic review regarding the benefits and adverse events (AEs) of CBD in the treatment of schizophrenia, psychotic [...]
Lire la suiteLSD : microdoses festives Céline ZÜND Le Temps, mardi 28 janvier 2020 https://www.letemps.ch/societe/lsd-microdoses-festives?utm_campaign=article_traffic&utm_content=1580242382&utm_medium=social&utm_source=facebook&fbclid=IwAR3v1uDm_lCzk_Bb1XMeRzSxcxr-mHObGhhPeJVK-Fa0y6rczvc3DFJ3H78 La prise de LSD en petites quantités fait toujours plus d'adeptes, dans les milieux festifs, au travail ou en automédication. Or la recherche scientifique ne dispose pas de données fiables sur les véritables effets de cette substance, ni sur ses risques potentiels. Ursina s’est longtemps refusée à la tentation d’accompagner ses nuits festives de substances chimiques. «J’avais peur du mauvais trip», dit la Zurichoise de 40 ans, casquette et bomber satiné. Jusqu’à ce qu’elle entende parler du LSD en microdose. Elle se procure l’hallucinogène une première fois il y [...]
Lire la suiteTherapeutic Satisfaction and Subjective Effects of Different Strains of Pharmaceutical-Grade Cannabis Tibor M. Brunt, Marianne van Genugten, Kathrin Honer-Snoeken, Marco J. van de Velde, and Raymond J.M. Niesink Journal of Clinical Psychopharmacoly, 2014, 34, 344Y349 Doi : 10.1097/JCP.0000000000000129 Abstract : In The Netherlands, pharmaceutical-grade cultivated cannabis is distributed for medicinal purposes as commissioned by the Ministry of Health. Few studies have thus far described its therapeutic efficacy or subjective (adverse) effects in patients. The aims of this study are to assess the therapeutic satisfaction within a group of patients using prescribed pharmaceutical-grade cannabis and to compare the subjective effects among the available strains with special [...]
Lire la suiteEntheogens Katie Givens Kime Institute of Practical Theology, University of Bern, Bern, Switzerland in D. A. Leeming (ed.), "Encyclopedia of Psychology and Religion", # Springer-Verlag GmbH Germany, part of Springer Nature 2018 Doi : 10.1007/978-3-642-27771-9_200181-1 Entheogen is a term coined in the late 1970s by a group of botanists and scholars which refers to any psychoactive agent which allows for “generating the divine within” (Ruck et al. 1979). Entheogens are psychedelic substances which, in adequate dosage under supportive conditions, are known to facilitate visionary, mystical, and/or spiritual experiences. Such substances include psilocybin, peyote, LSD (lysergic acid diethylamide), ibogaine, and ayahuasca. Typically of plant origin, entheogens are [...]
Lire la suiteL’huile de chanvre contient-elle du THC et du CBD ? Newsweed, 11 février 2020 Aurélien BERNARD https://www.newsweed.fr/huile-chanvre-contient-thc-cbd/ L’huile de chanvre, extraite des graines, est une source précieuse d’omega 3 et 6 et de nutriments dans l’alimentation quotidienne. Sa valeur nutritionnelle et thérapeutique pourrait néanmoins aussi être attribuée à sa composition en cannabinoïdes qui, si faiblement présents, existent quand même. Dans une étude de 2019, plusieurs cannabinoïdes ont été détectés dans l’huile de graines de chanvre et permettent de déterminer des différences dans leur composition chimique. Bien que le CBDA et le CBD soient prédominants dans les dix huiles étudiées, 20 autres cannabinoïdes «mineurs» ont été [...]
Lire la suiteRoyaume-Uni : ultimatum pour les fabricants d’huile CBD, Newsweed, 13 février 2020, Aurélien BERNARD
Royaume-Uni : ultimatum pour les fabricants d’huile CBD Newsweed, 13 février 2020 Aurélien BERNARD https://www.newsweed.fr/royaume-uni-ultimatum-huile-cbd/ La Food Standards Agency (FSA), agence britannique responsable de la protection de la santé publique dans l’alimentation, a publié ses tout premiers conseils de sécurité pour les consommateurs concernant l’huile de CBD vendue au Royaume-Uni, ainsi qu’un avertissement aux fabricants de produits à base de CBD. Conseils de sécurité alimentaire sur le CBD La FSA conseille aux femmes enceintes, qui allaitent ou aux personnes qui suivent un traitement médical de ne pas consommer de produits au CBD. Il est également conseillé aux adultes en bonne santé de bien réfléchir avant de [...]
Lire la suiteAssociation of Depression, Anxiety, and Trauma With Cannabis Use During Pregnancy Kelly C. Young-Wolff, PhD, MPH; Varada Sarovar, PhD; Lue-Yen Tucker, BA; Nancy C. Goler, MD; Stacey E. Alexeeff, PhD; Kathryn K. Ridout,MD, PhD; Lyndsay A. Avalos, PhD JAMA Network Open, 2020, 3, (2), e1921333. doi : 10.1001/jamanetworkopen.2019.21333 Introduction Prenatal cannabis use is increasing,1,2 and several qualitative studies3,4 indicate that pregnantwomen self-report using cannabis to manage stress and mood. However, few epidemiological studies have examined whether pregnant women with mental health disorders and trauma are at increased risk of using cannabis during pregnancy. Data from the Kaiser Permanente Northern California (KPNC) large integrated health care [...]
Lire la suiteAcute and chronic effects of cannabinoids on effort-related decision-making and reward learning: an evaluation of the cannabis ‘amotivational’ hypotheses Will Lawn, Tom P. Freeman, Rebecca A. Pope, Alyssa Joye, Lisa Harvey, Chandni Hindocha, Claire Mokrysz, Abigail Moss, Matthew B. Wall, Michael A.P. Bloomfield, Ravi K. Das, Celia J.A. Morgan, David J. Nutt, H. Valerie Curran Psychopharmacology, 2016, 233, 3537–3552 Doi : 10.1007/s00213-016-4383-x Abstract Rationale : Anecdotally, both acute and chronic cannabis use have been associated with apathy, amotivation, and other reward processing deficits. To date, empirical support for these effects is limited, and no previous studies have assessed both acute effects of Δ-9-tetrahydrocannabinol (THC) and [...]
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