Why Psychiatry Needs 3,4 Methylenedioxymeth-amphetamine : A Child Psychiatrist’s Perspective Ben SESSA Neurotherapeutics, 2017, 14, (3), 741-749. doi:10.1007/s13311-017-0531-1 Abstract Since the late 1980s the psychoactive drug 3,4-methylenedioxymethamphetamine (MDMA) has had a well-known history as the recreationally used drug ecstasy. What is less well known by the public is that MDMA started its life as a therapeutic agent and that in recent years an increasing amount of clinical research has been undertaken to revisit the drug’s medical potential. MDMA has unique pharmacological properties that translate well to its proposed agent to assist trauma-focused psychotherapy. Psychological trauma—especially that which arises early in life from child abuse—underpins many [...]
Lire la suiteCommon neural signatures of psychedelics : Frequency-specific energy changes and repertoire expansion revealed using connectome-harmonic decomposition Selen Atasoy, Jakub Vohryzek, Gustavo Deco, Robin L. Carhart-Harris, Morten L. Kringelbach Progress in Brain Research, 2018, Volume 242,97- https://doi.org/10.1016/bs.pbr.2018.08.009 ISSN 0079-6123 © 2018 Elsevier B.V. All rights reserved. Abstract The search for the universal laws of human brain function is still on-going but progress is being made. Here we describe the novel concepts of connectome harmonics and connectomeharmonic decomposition, which can be used to characterize the brain activity associated with any mental state. We use this new frequency-specific language to describe the brain activity elicited by psilocybin and LSD [...]
Lire la suiteThe expansion of the field of research on ayahuasca: Some reflections about the ayahuasca track at the 2010 MAPS “Psychedelic Science in the 21st Century” conference Beatriz Caiuby Labate, Clancy Cavnar International Journal of Drug Policy, 2011, 22, 174–178 doi:10.1016/j.drugpo.2010.09.002 A recent conference sponsored by the Multidisciplinary Association for Psychedelic Studies (MAPS) in collaboration with the Heffter Research Institute, the Beckley Foundation and the Council on Spiritual Practices held from April 15th to 18th 2010, in San José, USA (MAPS, 2010) united 90 presenters and 1100 participants with the goal of giving visibility to studies on the therapeutic potentials of psychedelics (psilocybin,MDMA,ibogaine, ayahuasca, etc.) [...]
Lire la suiteUne université de Houston teste la psilocybine pour la dépression résistante aux traitements - www.NEWSWEED.fr 22 octobre 2019 Aurélien BERNARD Dans la foulée de sa décriminalisation dans quelques villes des États-Unis (Oakland et Denver notamment), la psilocybine intéresse actuellement la communauté scientifique à la recherche de preuves d’efficacité thérapeutique. Des chercheurs du Science Health Center de l’Université du Texas à Houston (UTHealth) ont annoncé qu’ils étudiaient la psilocybine pour la dépression réfractaire aux traitements. PUBLICITE L’étude est inspirée par des recherches scientifiques antérieures qui suggèrent que la psilocybine agit pour créer de nouveaux circuits mentaux. Une étude de 2012 a conclu que la substance pouvait permettre [...]
Lire la suiteHallucinogens and Their Therapeutic Use : A Literature Review Matthew J. BEGOLA, Jason E. SCHILLERSTROM Journal of Psychiatric Practice, 2019, 25, (5), 334–346 Doi : 10.1097/PRA.0000000000000409 The exploration of possible therapeutic benefitsof hallucinogenic substances has undergone a revitalization in the past decade. This literature review investigated the published literature regarding the psychotherapeutic uses of hallucinogens in psychiatric disorders. The results showed that a variety of substances have been evaluated in the treatment of psychiatric disorders, including ayahuasca, ibogaine, ketamine, lysergic acid diethylamide, 3,4-methylenedioxymethamphetamine, and psilocybin. The conditions treated ranged from depression to autism, with the largest volume of research dedicated to substance use disorders. [...]
Lire la suiteThe Effects of Acutely Administered 3,4-Methylenedioxymethamphetamine on Spontaneous Brain Function in Healthy Volunteers Measured with Arterial Spin Labeling and Blood Oxygen Level–Dependent Resting State Functional Connectivity Robin L. Carhart-Harris, Kevin Murphy, Robert Leech, David Erritzoe, Matthew B. Wall, Bart Ferguson, Luke T.J. Williams, Leor Roseman, Stefan Brugger, Ineke De Meer, Mark Tanner, Robin Tyacke, Kim Wolff, Ajun Sethi, Michael A.P. Bloomfield, Tim M. Williams, Mark Bolstridge, Lorna Stewart, Celia Morgan, Rexford D. Newbould, Amanda Feilding, H. Val Curran, and David J. Nutt Biological Psychiatry, 2015, 78, 554-562. http://dx.doi.org/10.1016/j.biopsych.2013.12.015 ABSTRACT BACKGROUND : The compound 3,4-methylenedioxymethamphetamine (MDMA) is a potent monoamine releaser that produces an acute euphoria in most individuals. METHODS : [...]
Lire la suiteIACM-Bulletin du 22 Octobre 2019 Dixième conférence de l'IACM sur les cannabinoïdes en médecine à Berlin Science/Homme: Selon une vaste enquête, une grande proportion de patients souffrant de douleur sont en mesure de réduire ou d'arrêter l'utilisation d'opioïdes Science/Homme: Selon une étude ouverte, le CBD pourrait avoir un effet positif pour la survie pour les patients atteints d’un glioblastome Science/Animal: Comment le CBD atténue les effets psychologiques du THC Science/Homme: Amélioration clinique de la maladie inflammatoire de l'intestin lors d’une étude d'observationnelle Science/Homme: Lors d’une petite étude une prise orale de cannabis a permis [...]
Lire la suiteBibliographie "Salvia divinorum" Pharmacologie, Ethnopharmacologie, Neurophysiologie, Usages Thérapeutiques..., GRECC, Dr Christian Sueur, octobre 2019. Salvia divinorum : généralités, usages, sociologie.....................................................................................1 Salvia divinorum, Salvinorin A : Neurophysiologie..................................................................................4 Salvinorin A : Pharmacologie.....................................................................................................................7 Salvia divinorum et chamanisme..............................................................................................................11 Salvia divinorum et psychiatrie................................................................................................................12 Salvia divinorum et thérapeutique...........................................................................................................13
Lire la suiteThe Therapeutic Use of Ayahuasca Beatriz Caiuby LABATE, Clancy CAVNAR Editors, Springer-Verlag, Berlin, Heidelberg, 2014 Foreword Ancient Medicine and the Modern World Ayahuasca, the ‘‘great medicine’’ of the Amazon rain forest, was, for millennia, entirely unknown to Western Euro-American civilization. While first scientifically identified, catalogued, and recorded in the mid-nineteenth century by the English botanist and explorer Richard Spruce, it had earlier been the object of brutal suppression by Spanish and Portuguese invaders of the New World who attempted to violently extinguish its ceremonial use by the indigenous people of the Amazon. Employing the harshest measures of the Inquisition, in 1616, the Catholic Church [...]
Lire la suiteAssessment of the Psychotherapeutic Effects of Ritual Ayahuasca Use on Drug Dependency : A Pilot Study Xavier Fernández, Rafael Guimarães dos Santos, Marta Cutchet, Sabela Fondevila, Débora González, Miguel Ángel Alcázar, Jordi Riba, José Carlos Bouso, Josep María Fábregas, Xavier Fernández, Rafael Guimarães dos Santos in "The Therapeutic Use of Ayahuasca", Chapter 11, 183-196 Beatriz Caiuby LABATE, Clancy CAVNAR Editors, Springer-Verlag, Berlin, Heidelberg, 2014 First Online: 23 November 2013 Abstract Using personality, psychopathology, and neuropsychological assessment instruments, our team assessed the therapeutic effects of an ayahuasca ritual treatment. Data was collected at the Institute of Applied Amazonian Ethnopsychology (IDEAA), in the Brazilian Amazon Basin. Psychological assessments [...]
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